ASTM E3002-15 - Standard Practice for Assessing the Comparative Efficacy of Products Used for the Decontamination of Chemical Warfare Agents (CWAs) on Skin
Standard Practice for Assessing the Comparative Efficacy of Products Used for the Decontamination of Chemical Warfare Agents (CWAs) on Skin
| Standard number: | E3002-15 |
| Released: | 15.06.2015 |
| Status: | Active |
| Pages: | 5 |
| Section: | 15.08 |
| Keywords: | acetylcholinesterase; Chemical Warfare Agents (CWAs); decontamination and neutralization; GA Tabun; GB Sarin; GD Soman; GF Cyclohexyl Sarin; HD Mustard; in-vitro; in-vivo; LD50; nerve agents; neutralization; protective ratio; organophosphate (OP); skin; VX Nerve Agent; |
1.1 This practice establishes an in-vivo method for assessing the comparative efficacy of products used for the decontamination of chemical warfare agents (CWAs) on the skin.
1.2 This practice provides a quantitative efficacy comparison of different skin decontamination products.
1.3 To minimize the number of animals used, this in-vivo practice should be performed only after rigorous in-vitro studies of the candidate decontaminant, which can show the implied claims including chemical neutralization, decontamination studies on surfaces and appropriate testing such as cytotoxicity.
1.4 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.
1.5 This standard does not purport to address all of the safety concerns, if any, associated with the use of decontamination products or CWAs. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.