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>ISO Standards>ISO 19290:2021-Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS
immediate downloadReleased: 2021
ISO 19290:2021-Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS

ISO 19290:2021

ISO 19290:2021-Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS

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Standard´s number:ISO 19290:2021
Pages:14
Edition:2
Released:2021
DESCRIPTION

ISO 19290:2021


This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
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