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>BSI Standards >13 ENVIRONMENT. HEALTH PROTECTION. SAFETY>13.060 Water quality>13.060.50 Examination of water for chemical substances>BS EN ISO 13646:2025 Water quality. Determination of selected estrogens in whole water samples. Method using solid phase extraction (SPE) followed by liquid chromatography (LC) or gas chromatography (GC) coupled to mass spectrometry (MS) detection
immediate downloadReleased: 2025-10-16
BS EN ISO 13646:2025 Water quality. Determination of selected estrogens in whole water samples. Method using solid phase extraction (SPE) followed by liquid chromatography (LC) or gas chromatography (GC) coupled to mass spectrometry (MS) detection

BS EN ISO 13646:2025

Water quality. Determination of selected estrogens in whole water samples. Method using solid phase extraction (SPE) followed by liquid chromatography (LC) or gas chromatography (GC) coupled to mass spectrometry (MS) detection

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Standard number:BS EN ISO 13646:2025
Pages:72
Released:2025-10-16
ISBN:978 0 539 21800 8
Status:Standard

BS EN ISO 13646:2025 - Comprehensive Guide to Water Quality Analysis

Introducing the BS EN ISO 13646:2025, a pivotal standard for professionals in the field of environmental science and water quality analysis. This document is an essential resource for those seeking to accurately determine the presence of selected estrogens in whole water samples. Released on October 16, 2025, this standard is a testament to the latest advancements in analytical methodologies.

Overview of the Standard

The BS EN ISO 13646:2025 provides a detailed methodology for the determination of selected estrogens in water samples. This is achieved through a sophisticated process involving solid phase extraction (SPE) followed by either liquid chromatography (LC) or gas chromatography (GC), both of which are coupled with mass spectrometry (MS) detection. This combination of techniques ensures high precision and reliability in detecting even trace amounts of estrogens, which are critical for assessing water quality and environmental safety.

Key Features and Benefits

  • Standard Number: BS EN ISO 13646:2025
  • Pages: 72
  • ISBN: 978 0 539 21800 8
  • Status: Standard

This standard is meticulously crafted to cater to the needs of environmental scientists, laboratory technicians, and regulatory bodies. It provides a comprehensive framework that ensures consistency and accuracy in water quality testing, which is crucial for maintaining public health and environmental integrity.

Why Choose BS EN ISO 13646:2025?

The determination of estrogens in water is a critical aspect of environmental monitoring. Estrogens, even in minute concentrations, can have significant ecological and health impacts. The BS EN ISO 13646:2025 standard offers a robust and scientifically validated approach to detecting these compounds, ensuring that water quality assessments are both reliable and reproducible.

By employing advanced techniques such as SPE, LC, GC, and MS, this standard provides a comprehensive solution that meets the rigorous demands of modern analytical chemistry. These methods are not only effective but also adaptable, allowing for the detection of a wide range of estrogenic compounds in various water matrices.

Applications and Implications

The applications of the BS EN ISO 13646:2025 are vast and varied. It is an invaluable tool for:

  • Environmental Monitoring: Ensuring that water bodies are free from harmful estrogenic compounds.
  • Regulatory Compliance: Assisting industries and municipalities in meeting environmental regulations and standards.
  • Research and Development: Facilitating advanced research in environmental science and analytical chemistry.

With its comprehensive approach, this standard not only aids in the protection of aquatic ecosystems but also supports public health initiatives by ensuring safe and clean water supplies.

Structure and Content

Spanning 72 pages, the BS EN ISO 13646:2025 is structured to provide clear and concise guidance on the analytical procedures. It includes detailed sections on:

  • Sample Preparation: Guidelines for collecting and preparing water samples for analysis.
  • Analytical Techniques: Step-by-step instructions for SPE, LC, GC, and MS methodologies.
  • Data Interpretation: Methods for analyzing and interpreting results to ensure accurate conclusions.
  • Quality Control: Procedures for maintaining the integrity and reliability of analytical results.

Each section is designed to provide users with the knowledge and tools necessary to perform high-quality water analysis, making it an indispensable resource for professionals in the field.

Conclusion

The BS EN ISO 13646:2025 is more than just a standard; it is a comprehensive guide that empowers professionals to conduct precise and reliable water quality assessments. By adopting this standard, you are ensuring that your analytical practices are aligned with the latest scientific advancements and regulatory requirements.

Whether you are involved in environmental monitoring, regulatory compliance, or scientific research, the BS EN ISO 13646:2025 is an essential addition to your professional toolkit. Embrace the future of water quality analysis with this cutting-edge standard and contribute to a safer, healthier environment for all.

DESCRIPTION

BS EN ISO 13646:2025


This standard BS EN ISO 13646:2025 Water quality. Determination of selected estrogens in whole water samples. Method using solid phase extraction (SPE) followed by liquid chromatography (LC) or gas chromatography (GC) coupled to mass spectrometry (MS) detection is classified in these ICS categories:
  • 13.060.50 Examination of water for chemical substances
This document specifies methods for the determination of five selected estrogens in whole water samples listed in Table 1 (see Clause 4). The methods are based on solid-phase extraction (SPE; disk or cartridge) followed by liquid or gas chromatography-mass spectrometry detection (tandem mass spectrometry or high resolution mass spectrometry). Depending on the sample preparation chosen, the sample preparation can be applicable to the analysis of selected estrogens in drinking water, groundwater and surface water containing suspended particulate matter (SPM) up to 500 mg/l, dissolved organic carbon (DOC) content up to 14 mg/l (whole water samples). The lower application range defined as verified limit of quantification can vary depending on the methods, the sensitivity of the equipment used and the matrix of the sample. The range is 0,006 ng/l to 1 ng/l for 17alpha-ethinylestradiol (EE2) and 0,038 ng/l to 1 ng/l for the other estrogens in drinking water, ground water and surface water. The upper limit of the working range is approximately tens of nanograms per litre. For application that targets the measurements of very low level concentrations (between the lowest LOQ and 0,1 ng/l), every single step of the procedure becomes critical. The methods can be used to determine further estrogens or hormones in other types of water, for example treated wastewater, if accuracy has been tested and verified for each case as well as storage conditions of both samples and reference solutions have been validated.