BS EN ISO 17099:2017

This standard BS EN ISO 17099:2017 Radiological protection. Performance criteria for laboratories using the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry is classified in these ICS categories:

• 13.280 Radiation protection

This International Standard addresses the following:

1. confidentiality of personal information for the customer and the laboratory;

2. laboratory safety requirements;

3. radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;

4. performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;

5. scoring criteria;

6. conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;

7. reporting of results;

8. quality assurance and quality control;

9. informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.