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Homepage>ASTM Standards>17>17.240>ASTM E1939-17R22 - Standard Practice for Blood Irradiation Dosimetry
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Released: 01.06.2022

ASTM E1939-17R22 - Standard Practice for Blood Irradiation Dosimetry

Standard Practice for Blood Irradiation Dosimetry

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Standard number:E1939-17R22
Keywords:absorbed dose; absorbed-dose mapping; blood; blood components; blood products; blood irradiation; bremsstrahlung; dosimeter; dosimetry system; gamma radiation; irradiator; ionizing radiation; measurement quality assurance plan; measurement uncertainty; radiation-sensitive indicators; reference-standard dosimeter; routine dosimeter; transfer-standard dosimeter; ICS 17.240; X-radiation;

1.1 This practice outlines the irradiator installation qualification program and the dosimetric procedures to be followed during operational qualification and performance qualification of the irradiator. Procedures for the routine radiation processing of blood product (blood and blood components) are also given. If followed, these procedures will help ensure that blood product exposed to gamma radiation or X-radiation (bremsstrahlung) will receive absorbed doses with a specified range.

1.2 This practice covers dosimetry for the irradiation of blood product for self-contained irradiators (free-standing irradiators) utilizing radionuclides such as 137Cs and   60Co, or X-radiation (bremsstrahlung). The absorbed dose range for blood irradiation is typically 15 Gy to 50 Gy.

1.3 The photon energy range of X-radiation used for blood irradiation is typically from 40 keV to 300 keV.

1.4 This practice also covers the use of radiation-sensitive indicators for the visual and qualitative indication that the product has been irradiated (see ISO/ASTM Guide 51539).

1.5 This document is one of a set of standards that provides recommendations for properly implementing dosimetry in radiation processing and describes a means of achieving compliance with the requirements of ISO/ASTM Practice 52628 for dosimetry performed for blood irradiation. It is intended to be read in conjunction with ISO/ASTM Practice 52628.

1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.

1.7 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.